Haematology and immunology
Haemoglobin, g/dL
Laboratory haematology analyser (reference) compared with Point of care haemoglobin meter B (central laboratory setting). 56 paired results.
Compare it with the other comparisons in the explorer
Comparison line
The new system reads 12.5% lower than the old system on average. The comparison line (Passing-Bablok) has a slope of 1.13 (95% interval 1 to 1.325) and an intercept of -2.252.
Fig. 1. The comparison line against the line of no change, over the range of the decision limits (8, 12, 13 g/dL). Dots mark where each line meets each limit; the gap between them is the bias at that limit.
Crossing each limit
Results that fall on the other side of a decision limit on the new system than on the old, read as if the new system had replaced the old, against the number repeat testing on one unchanged system would move. The program reports the count across all limits together.
All decision limits together (8, 12, 13 g/dL)
Crossed between the two systems: 16
Expected from repeat testing alone: about 32
Grade and warnings
- Re-test band: Indicative: 56 pairs, below the 100-pair protocol minimum.
- Band half-width around each limit: 1.38%.
- Results re-tested on data the band was not fitted to, median: 14%.
- Repeat-test imprecision: supplied by the study, precision file (patient-sample replicates, 5 per sample), the larger of the two systems.
- Note: Fewer than 5 results crossed beyond what repeat testing alone would move; excess caught is not meaningful here.
Source
Data: Huub Gelderblom (2016). Performance characteristics of three point of care hemoglobin meters in Durban-2.xlsx. figshare. doi:10.6084/m9.figshare.3119449 (opens in a new tab). Licence: CC BY 4.0 (opens in a new tab). Supplement to Jaggernath M, Naicker R, Madurai S, Brockman MA, Ndung'u T, Gelderblom HC (2016). PLoS One. doi:10.1371/journal.pone.0152184 (opens in a new tab); PMC4821624 (opens in a new tab). Re-analysed by NakedSignal. The deposit names the systems.
Show the numbers
| Field | Value |
|---|---|
| Paired results used | 56 |
| Comparison line slope | 1.130435 |
| Slope, 95% interval | 1 to 1.325137 |
| Comparison line intercept | -2.252174 |
| Mean difference, new minus old, as % of old | -12.5 |
| Decision limits (g/dL) | 8, 12, 13 |
| Crossed between the two systems | 16 |
| Expected from repeat testing alone | 32.36 |
| Band half-width (%) | 1.38 |
| Re-tested, unseen data, median (%) | 14.29 |
| Re-tested, unseen data, range (%) | 8.93 to 17.86 |
| Excess caught, line and band (%) | none |
| Excess caught, line alone (%) | none |