Chemistry
LDL cholesterol, mg/dL (from mmol/L x 38.67)
Central lab analyser, directly measured LDL cholesterol replaced by LDL cholesterol calculated by the Friedewald equation. 1,298 paired results.
Compare it with the other comparisons in the explorer
Comparison line
The new system reads 14.7% lower than the old system on average. The comparison line has a slope of 0.962 (95% interval 0.949 to 0.974) and an intercept of -7.529.
No decision lines configured for this analyte and unit; comparison only (no switch table, no re-test band)
Crossing each limit
No crossing count: the program had no decision limits for this comparison.
Grade and warnings
- No decision lines configured for this analyte and unit; comparison only (no switch table, no re-test band)
- A secondary comparison: a calculated value against a measured one, shown for completeness.
Source
Dintshi M, Kone N, Khoza S (2022). Comparison of measured LDL cholesterol with calculated LDL-cholesterol using the Friedewald and Martin-Hopkins formulae in diabetic adults at Charlotte Maxeke Johannesburg Academic Hospital/NHLS Laboratory. PLoS One. doi:10.1371/journal.pone.0277981 (opens in a new tab); PMC9749991 (opens in a new tab). Licence: CC BY 4.0 (opens in a new tab). Changes: Paired results re-analysed by NakedSignal's program; instruments described generically; only derived results are shown. The deposit names the systems.
Show the numbers
| Field | Value |
|---|---|
| Paired results used | 1,298 |
| Comparison line slope | 0.96225 |
| Slope, 95% interval | 0.949346 to 0.973786 |
| Comparison line intercept | -7.528733 |
| Mean difference, new minus old, as % of old | -14.7 |
| Decision limits (mg/dL (from mmol/L x 38.67)) | none |
| Crossed after the change | none |
| Expected from repeat testing alone | none |
| Band half-width (%) | none |
| Re-tested, unseen data, median (%) | none |
| Re-tested, unseen data, range (%) | none |
| Excess caught, line and band (%) | none |
| Excess caught, line alone (%) | none |