Chemistry
LDL cholesterol, mg/dL (from mmol/L x 38.67)
Central lab analyser, directly measured LDL cholesterol replaced by LDL cholesterol calculated by the Martin-Hopkins equation. 1,301 paired results.
Compare it with the other comparisons in the explorer
Comparison line
The new system reads 10% lower than the old system on average. The comparison line has a slope of 0.956 (95% interval 0.942 to 0.97) and an intercept of -4.565.
No decision lines configured for this analyte and unit; comparison only (no switch table, no re-test band)
Crossing each limit
No crossing count: the program had no decision limits for this comparison.
Grade and warnings
- No decision lines configured for this analyte and unit; comparison only (no switch table, no re-test band)
- A secondary comparison: a calculated value against a measured one, shown for completeness.
Source
Dintshi M, Kone N, Khoza S (2022). Comparison of measured LDL cholesterol with calculated LDL-cholesterol using the Friedewald and Martin-Hopkins formulae in diabetic adults at Charlotte Maxeke Johannesburg Academic Hospital/NHLS Laboratory. PLoS One. doi:10.1371/journal.pone.0277981 (opens in a new tab); PMC9749991 (opens in a new tab). Licence: CC BY 4.0 (opens in a new tab). Changes: Paired results re-analysed by NakedSignal's program; instruments described generically; only derived results are shown. The deposit names the systems.
Show the numbers
| Field | Value |
|---|---|
| Paired results used | 1,301 |
| Comparison line slope | 0.955959 |
| Slope, 95% interval | 0.942207 to 0.970343 |
| Comparison line intercept | -4.565491 |
| Mean difference, new minus old, as % of old | -10.034 |
| Decision limits (mg/dL (from mmol/L x 38.67)) | none |
| Crossed after the change | none |
| Expected from repeat testing alone | none |
| Band half-width (%) | none |
| Re-tested, unseen data, median (%) | none |
| Re-tested, unseen data, range (%) | none |
| Excess caught, line and band (%) | none |
| Excess caught, line alone (%) | none |